Neuroglobin Can Prevent or Reverse Glaucomatous Progression in DBA/2J Mice
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چکیده
منابع مشابه
Neuroglobin Can Prevent or Reverse Glaucomatous Progression in DBA/2J Mice
Mitochondrial dysfunction is responsible for hereditary optic neuropathies. We wished to determine whether preserving mitochondrial bioenergetics could prevent optic neuropathy in a reliable model of glaucoma. DBA/2J mice exhibit elevated intraocular pressure, progressive degeneration of their retinal ganglion cells, and optic neuropathy that resembles glaucoma. We established that glaucoma in ...
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ژورنال
عنوان ژورنال: Molecular Therapy - Methods & Clinical Development
سال: 2017
ISSN: 2329-0501
DOI: 10.1016/j.omtm.2017.04.008